It was built in 1615 by the architect Pietre De Marino and annexed to the already existing monastery (and work of the same architect) in which lived the Brasilian Nuns, that became the Benedictines. In the following century a long period of restoration began, work of the architect Giovan Battista Broggia, which ended in 1780. Later, during the “French decade “ the order was suppressed, forcing the nuns to transfer in San Gregorio Armeno. The Church was deprived of some works of art and the monastery destinated to accomodate the infantry.
Subsequently ,with the return of the Bourbon in the Kingdom, the Church was entrusted to the Congregation of Banco’s Officers, while after the Unity of Italy the monastery was converted into barracks of the Carabinieri.

Reachable thanks to the flight of steps built in 1867, the facade was realised in stone and bricks and is divided in two orders. The second order has 3 big windows framed by pilasters, while the first one enters a portico on which the chorus of the nuns is placed. The interior has a single nave with three chapels on each side and presents a valuable altar of the Eighteenth century. On the walls of the apse area there are three paintings: on the left wall St. Potito that saves Agnes, the possessed daughter of Antonino (Giacinto Diano,1784), in the centre the “ Martyrdom of St. Potito” (Nicolò De Simone ,1654) and on the right wall St. Potito that tears down an idol. In the first chapel on the right there is a valuable painting by Luca Giordano, dated between 1663 and 1665, depicting the Madonna del Rosario (Lady of the Rosary). In the third chapel on the right,instead, is preseved another painting representing the Immaculate, work of Giacinto Diano, dated in 1791. In the first left side chapel there is a painting depicting the Calvary, anonymous work of the XVII century.

On the second left side chapel a laudable decoration has been realised in stucco, reproducing Saint Gaetano da Thiene and a group of little angels, likely coeval to the restoration of thevroom, happened in 1880, as indicated by an iscription on the floor (some sources indicate as possible author a certain D. Caponello, name indicated by the Book of the Rule held in hand by one of the angels). Finally, the third left chapel preserves a painting by Andrea Vaccaro,portraying the Virgin between Saints Anthony and Rocco. In the sacristy are placed, instead the paintings of Pacecco De Rosa, with the Virgin of Purity to whom the Saints Antonio and Giuseppe introduce four brothers among the souls of the Purgatory. Another portraying of the Virgin Mary and the Saints with the sacraments among the souls of Purgatory is attribuited to Domenico Mondo.